HEPATIC SOD1 GENE EXPRESSION CHANGES IN THE NAFLD PATHOGENESIS IN OBESITY

Steatosis in the liver in obesity increases the work of mitochondria to utilize excess lipids. An overload of β-oxidation of fatty acids, the tricarboxylic acid cycle, and oxidative phosphorylation leads to a decrease in ATP and an increase in the formation of reactive oxygen species. Normally, mito...

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Main Authors: A. A. Komar, D. A. Shunkina (Skuratovsvkaia), M. A. Vulf, H. Q. Vu, N. M. Todosenko, P. A. Zatolokin, E. V. Kirienkova, N. D. Gazatova, L. S. Litvinova
Format: article
Language:RU
Published: SPb RAACI 2021
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Online Access:https://doaj.org/article/e1851aa1076b4b299bd68be2c8bc8d4b
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