HEPATIC SOD1 GENE EXPRESSION CHANGES IN THE NAFLD PATHOGENESIS IN OBESITY
Steatosis in the liver in obesity increases the work of mitochondria to utilize excess lipids. An overload of β-oxidation of fatty acids, the tricarboxylic acid cycle, and oxidative phosphorylation leads to a decrease in ATP and an increase in the formation of reactive oxygen species. Normally, mito...
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Auteurs principaux: | A. A. Komar, D. A. Shunkina (Skuratovsvkaia), M. A. Vulf, H. Q. Vu, N. M. Todosenko, P. A. Zatolokin, E. V. Kirienkova, N. D. Gazatova, L. S. Litvinova |
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Format: | article |
Langue: | RU |
Publié: |
SPb RAACI
2021
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Accès en ligne: | https://doaj.org/article/e1851aa1076b4b299bd68be2c8bc8d4b |
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