Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
Abstract Soymilk allergy is caused by cross‐reaction of either birch Bet v 1–specific or alder Aln g 1–specific IgE to soybean Gly m 4, which belongs to pathogenesis‐related protein‐10 (PR‐10) family. Gly m 4–specific IgE test identifies soybean allergy patients with high sensitivity. In this case s...
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2021
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oai:doaj.org-article:e18cf4357e304d8bbad33495a73987872021-11-08T15:10:52ZPositive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy2574-459310.1002/cia2.12177https://doaj.org/article/e18cf4357e304d8bbad33495a73987872021-10-01T00:00:00Zhttps://doi.org/10.1002/cia2.12177https://doaj.org/toc/2574-4593Abstract Soymilk allergy is caused by cross‐reaction of either birch Bet v 1–specific or alder Aln g 1–specific IgE to soybean Gly m 4, which belongs to pathogenesis‐related protein‐10 (PR‐10) family. Gly m 4–specific IgE test identifies soybean allergy patients with high sensitivity. In this case study, we found that CD203c expression–based basophil activation test (CD203c‐BAT) with soymilk protein became positive in the three cases of Gly m 4–related soymilk allergy at the concentrated of 1 μg/ml, but not in the control subjects. CD203c‐BAT may possibly be useful as a diagnostic tool to identify patients with soymilk allergy.Tokiko YoshidaYuko ChinukiShingo MatsukiEishin MoritaWileyarticleCD203c expression–based basophil activation testGly m 4pollen‐food allergy syndromesoybean allergysoymilk allergyDermatologyRL1-803Immunologic diseases. AllergyRC581-607ENJournal of Cutaneous Immunology and Allergy, Vol 4, Iss 5, Pp 128-131 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
CD203c expression–based basophil activation test Gly m 4 pollen‐food allergy syndrome soybean allergy soymilk allergy Dermatology RL1-803 Immunologic diseases. Allergy RC581-607 |
spellingShingle |
CD203c expression–based basophil activation test Gly m 4 pollen‐food allergy syndrome soybean allergy soymilk allergy Dermatology RL1-803 Immunologic diseases. Allergy RC581-607 Tokiko Yoshida Yuko Chinuki Shingo Matsuki Eishin Morita Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy |
description |
Abstract Soymilk allergy is caused by cross‐reaction of either birch Bet v 1–specific or alder Aln g 1–specific IgE to soybean Gly m 4, which belongs to pathogenesis‐related protein‐10 (PR‐10) family. Gly m 4–specific IgE test identifies soybean allergy patients with high sensitivity. In this case study, we found that CD203c expression–based basophil activation test (CD203c‐BAT) with soymilk protein became positive in the three cases of Gly m 4–related soymilk allergy at the concentrated of 1 μg/ml, but not in the control subjects. CD203c‐BAT may possibly be useful as a diagnostic tool to identify patients with soymilk allergy. |
format |
article |
author |
Tokiko Yoshida Yuko Chinuki Shingo Matsuki Eishin Morita |
author_facet |
Tokiko Yoshida Yuko Chinuki Shingo Matsuki Eishin Morita |
author_sort |
Tokiko Yoshida |
title |
Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy |
title_short |
Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy |
title_full |
Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy |
title_fullStr |
Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy |
title_full_unstemmed |
Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy |
title_sort |
positive basophil activation test with soymilk protein identifies gly m 4–related soymilk allergy |
publisher |
Wiley |
publishDate |
2021 |
url |
https://doaj.org/article/e18cf4357e304d8bbad33495a7398787 |
work_keys_str_mv |
AT tokikoyoshida positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy AT yukochinuki positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy AT shingomatsuki positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy AT eishinmorita positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy |
_version_ |
1718442190489780224 |