Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy

Abstract Soymilk allergy is caused by cross‐reaction of either birch Bet v 1–specific or alder Aln g 1–specific IgE to soybean Gly m 4, which belongs to pathogenesis‐related protein‐10 (PR‐10) family. Gly m 4–specific IgE test identifies soybean allergy patients with high sensitivity. In this case s...

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Autores principales: Tokiko Yoshida, Yuko Chinuki, Shingo Matsuki, Eishin Morita
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Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/e18cf4357e304d8bbad33495a7398787
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spelling oai:doaj.org-article:e18cf4357e304d8bbad33495a73987872021-11-08T15:10:52ZPositive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy2574-459310.1002/cia2.12177https://doaj.org/article/e18cf4357e304d8bbad33495a73987872021-10-01T00:00:00Zhttps://doi.org/10.1002/cia2.12177https://doaj.org/toc/2574-4593Abstract Soymilk allergy is caused by cross‐reaction of either birch Bet v 1–specific or alder Aln g 1–specific IgE to soybean Gly m 4, which belongs to pathogenesis‐related protein‐10 (PR‐10) family. Gly m 4–specific IgE test identifies soybean allergy patients with high sensitivity. In this case study, we found that CD203c expression–based basophil activation test (CD203c‐BAT) with soymilk protein became positive in the three cases of Gly m 4–related soymilk allergy at the concentrated of 1 μg/ml, but not in the control subjects. CD203c‐BAT may possibly be useful as a diagnostic tool to identify patients with soymilk allergy.Tokiko YoshidaYuko ChinukiShingo MatsukiEishin MoritaWileyarticleCD203c expression–based basophil activation testGly m 4pollen‐food allergy syndromesoybean allergysoymilk allergyDermatologyRL1-803Immunologic diseases. AllergyRC581-607ENJournal of Cutaneous Immunology and Allergy, Vol 4, Iss 5, Pp 128-131 (2021)
institution DOAJ
collection DOAJ
language EN
topic CD203c expression–based basophil activation test
Gly m 4
pollen‐food allergy syndrome
soybean allergy
soymilk allergy
Dermatology
RL1-803
Immunologic diseases. Allergy
RC581-607
spellingShingle CD203c expression–based basophil activation test
Gly m 4
pollen‐food allergy syndrome
soybean allergy
soymilk allergy
Dermatology
RL1-803
Immunologic diseases. Allergy
RC581-607
Tokiko Yoshida
Yuko Chinuki
Shingo Matsuki
Eishin Morita
Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
description Abstract Soymilk allergy is caused by cross‐reaction of either birch Bet v 1–specific or alder Aln g 1–specific IgE to soybean Gly m 4, which belongs to pathogenesis‐related protein‐10 (PR‐10) family. Gly m 4–specific IgE test identifies soybean allergy patients with high sensitivity. In this case study, we found that CD203c expression–based basophil activation test (CD203c‐BAT) with soymilk protein became positive in the three cases of Gly m 4–related soymilk allergy at the concentrated of 1 μg/ml, but not in the control subjects. CD203c‐BAT may possibly be useful as a diagnostic tool to identify patients with soymilk allergy.
format article
author Tokiko Yoshida
Yuko Chinuki
Shingo Matsuki
Eishin Morita
author_facet Tokiko Yoshida
Yuko Chinuki
Shingo Matsuki
Eishin Morita
author_sort Tokiko Yoshida
title Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
title_short Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
title_full Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
title_fullStr Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
title_full_unstemmed Positive basophil activation test with soymilk protein identifies Gly m 4–related soymilk allergy
title_sort positive basophil activation test with soymilk protein identifies gly m 4–related soymilk allergy
publisher Wiley
publishDate 2021
url https://doaj.org/article/e18cf4357e304d8bbad33495a7398787
work_keys_str_mv AT tokikoyoshida positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy
AT yukochinuki positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy
AT shingomatsuki positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy
AT eishinmorita positivebasophilactivationtestwithsoymilkproteinidentifiesglym4relatedsoymilkallergy
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