Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer

Silvia Liu et al. present LoopSeq, a synthetic long-read sequencing method that generates accurate long-read transcriptome data from short Illumina reads. As an example of possible applications, they use LoopSeq to investigate differential isoform expression, isoform-specific single nucleotide varia...

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Auteurs principaux: Silvia Liu, Indira Wu, Yan-Ping Yu, Michael Balamotis, Baoguo Ren, Tuval Ben Yehezkel, Jian-Hua Luo
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/e1cb04e6a8a1480383f9180ac1ea8876
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