Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

Bobo Wing-Yee Mok et al. observe that the Alpha (B.1.1.7) variant of SARS-CoV-2 exhibits increased competitive fitness over earlier lineages at lower doses in a hamster model of viral transmission. Their results suggest that the Alpha variant’s ability to initiate effective infection with a low dose...

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Bibliographic Details
Main Authors: Bobo Wing-Yee Mok, Honglian Liu, Shaofeng Deng, Jiayan Liu, Anna Jinxia Zhang, Siu-Ying Lau, Siwen Liu, Rachel Chun-Yee Tam, Conor J. Cremin, Timothy Ting-Leung Ng, Jake Siu-Lun Leung, Lam-Kwong Lee, Pui Wang, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Hung Chan, Kwok-Yung Yuen, Gilman Kit-Hang Siu, Honglin Chen
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/e1d11d48a5164a96b5e36a1d1ccb137f
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