Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps

Acute pancreatitis is a serious inflammatory disease, which is more severe in diabetic mice. Here the authors use mice lacking pancreatic acinar cell insulin receptors to show that this may be because insulin preserves glycolytic energy supply in acinar cell during pancreatitis, which prevents cytot...

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Autores principales: Jason I. E. Bruce, Rosa Sánchez-Alvarez, Maria Dolors Sans, Sarah A. Sugden, Nathan Qi, Andrew D. James, John A. Williams
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e209eb1710b64e959c279b5186b0a3a7
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