Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

Abstract The definition of the immunological response to Zika (ZIKV) infection in humans represents a key issue to identify protective profile useful for vaccine development and for pathogenesis studies. No data are available on the cellular immune response in the acute phase of human ZIKV infection...

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Main Authors: Eleonora Cimini, Concetta Castilletti, Alessandra Sacchi, Rita Casetti, Veronica Bordoni, Antonella Romanelli, Federica Turchi, Federico Martini, Nicola Tumino, Emanuele Nicastri, Angela Corpolongo, Antonino Di Caro, Gary Kobinger, Alimuddin Zumla, Maria Rosaria Capobianchi, Giuseppe Ippolito, Chiara Agrati
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e211ed0897014f748616b1a30cb3342e
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https://doaj.org/article/e211ed0897014f748616b1a30cb3342e

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