Optogenetic actuation in ChR2-transduced fibroblasts alter excitation-contraction coupling and mechano-electric feedback in coupled cardiomyocytes: a computational modeling study

With the help of the conventional electrical method and the growing optogenetic technology, cardiac fibroblasts (Fbs) have been verified to couple electrically with working myocytes and bring electrophysiological remodeling changes in them. The intrinsic properties of cardiac functional autoregulati...

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Bibliographic Details
Main Authors: Heqing Zhan, Zefeng Wang, Jialun Lin, Yuanbo Yu, Ling Xia
Format: article
Language:EN
Published: AIMS Press 2021
Subjects:
Online Access:https://doaj.org/article/e25f07685fa9492f85facc1812c7f02d
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