Optogenetic actuation in ChR2-transduced fibroblasts alter excitation-contraction coupling and mechano-electric feedback in coupled cardiomyocytes: a computational modeling study
With the help of the conventional electrical method and the growing optogenetic technology, cardiac fibroblasts (Fbs) have been verified to couple electrically with working myocytes and bring electrophysiological remodeling changes in them. The intrinsic properties of cardiac functional autoregulati...
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Autores principales: | Heqing Zhan, Zefeng Wang, Jialun Lin, Yuanbo Yu, Ling Xia |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
AIMS Press
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e25f07685fa9492f85facc1812c7f02d |
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