Miscibility and Solubility of Caffeine and Theophylline in Hydroxypropyl Methylcellulose

As amorphization may improve the solubility and bioavailability of a drug substance, the aim of this work was to assess to what extent the crystallinity of caffeine (CAF) and theophylline (TF) can be reduced by homogenization with a polymeric excipient. To realize this purpose, the physical mixtures...

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Autores principales: Edyta Leyk, Marek Wesolowski
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/e283acea960b40a68c5da3b18b9d866e
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