Miscibility and Solubility of Caffeine and Theophylline in Hydroxypropyl Methylcellulose
As amorphization may improve the solubility and bioavailability of a drug substance, the aim of this work was to assess to what extent the crystallinity of caffeine (CAF) and theophylline (TF) can be reduced by homogenization with a polymeric excipient. To realize this purpose, the physical mixtures...
Guardado en:
Autores principales: | Edyta Leyk, Marek Wesolowski |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e283acea960b40a68c5da3b18b9d866e |
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