A distinct holoenzyme organization for two-subunit pyruvate carboxylase

Pyruvate carboxylases are homotetrameric enzymes in eukaryotes and most bacteria. Here, the authors report the structure of an unusual two-subunit form of the enzyme from the Gram-negative bacterium Methylobacillus flagellates, revealing an unexpected α2β4stoichiometry.

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Autores principales: Philip H. Choi, Jeanyoung Jo, Yu-Cheng Lin, Min-Han Lin, Chi-Yuan Chou, Lars E. P. Dietrich, Liang Tong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e289b0f367274707a7bceab080bc093b
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