STAT1 signaling shields T cells from NK cell-mediated cytotoxicity

The JAK-STAT signaling pathway is important for cytokine responses and CD4 T-cell differentiation. Here the authors show that Stat1 also serves to protect CD4 T cells from natural killer cell-mediated killing, potentially by promoting the expression of Nlrc5 and MHC-I, to preserve the induction of e...

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Détails bibliographiques
Auteurs principaux: Yu Hui Kang, Amlan Biswas, Michael Field, Scott B. Snapper
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/e2c19505251948a095d635858a39e196
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