Food labeling issues for severe food allergic patients

Food allergy carries high importance and responsibility, affecting an estimated 220 million people worldwide. It is a frequent cause of food-induced anaphylaxis, a life-threatening condition requiring a toll of about one death per 50 million people a year worldwide. In order to help patients to iden...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Alessandro Fiocchi, MD, Davide Risso, PhD, Audrey DunnGalvin, PhD, Sandra N. González Díaz, MD, PhD, Linda Monaci, PhD, Vincenzo Fierro, MD, Ignacio J. Ansotegui, MD, PhD
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Food labeling Allergies Allergens VITAL Analytical methods Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/e2ddd10656a4408cb2a8cf2382a24961
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e2ddd10656a4408cb2a8cf2382a24961
record_format	dspace
spelling	oai:doaj.org-article:e2ddd10656a4408cb2a8cf2382a249612021-11-12T04:30:24ZFood labeling issues for severe food allergic patients1939-455110.1016/j.waojou.2021.100598https://doaj.org/article/e2ddd10656a4408cb2a8cf2382a249612021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1939455121000922https://doaj.org/toc/1939-4551Food allergy carries high importance and responsibility, affecting an estimated 220 million people worldwide. It is a frequent cause of food-induced anaphylaxis, a life-threatening condition requiring a toll of about one death per 50 million people a year worldwide. In order to help patients to identify allergenic foods and thus avoid anaphylactic reactions, 66 countries over the 5 continents require by law that allergenic ingredients must be declared when used in prepackaged foods. Unfortunately, the mandatory allergen list is not uniform, but varies among different countries. The widespread adoption of Precautionary Allergen Labeling (PAL) results in a proliferation of unregulated PALs with different informative statements. In this situation, the need of a scientific consensus on the definition of food allergy and the identification of a tolerable risk with routinely used detection assays, considering not only the eliciting dose but also the food source, is urgent. The aim of this manuscript is: 1) to draw a picture of the global situation in terms of PALs, and 2) to highlight new approaches that could aid in tackling the problem of regulating the labeling of allergens. These include the Voluntary Incidental Trace Allergen Labelling (VITAL) system, which intersects reference doses and labelling decisions, and a direct quantification of trace amounts of allergens at lower limit of detection (LOD) levels in the food itself through proteomics. We here highlight how, although with some limitations, the steady advances in proteomic approaches possess higher sensitivity than the recommended VITAL reference doses, allowing the identification of allergens at much lower LOD levels than VITAL. Considering that each assay used to detect allergen in food products carries method-specific issues, a more comprehensive and harmonized approach implementing both quantitative and qualitative methods could help overcoming the risk stratification approach and the overuse of PALs, offering promise as the field moves forward towards improving consumers’ quality of life.Alessandro Fiocchi, MDDavide Risso, PhDAudrey DunnGalvin, PhDSandra N. González Díaz, MD, PhDLinda Monaci, PhDVincenzo Fierro, MDIgnacio J. Ansotegui, MD, PhDElsevierarticleFood labelingAllergiesAllergensVITALAnalytical methodsImmunologic diseases. AllergyRC581-607ENWorld Allergy Organization Journal, Vol 14, Iss 10, Pp 100598- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Food labeling Allergies Allergens VITAL Analytical methods Immunologic diseases. Allergy RC581-607
spellingShingle	Food labeling Allergies Allergens VITAL Analytical methods Immunologic diseases. Allergy RC581-607 Alessandro Fiocchi, MD Davide Risso, PhD Audrey DunnGalvin, PhD Sandra N. González Díaz, MD, PhD Linda Monaci, PhD Vincenzo Fierro, MD Ignacio J. Ansotegui, MD, PhD Food labeling issues for severe food allergic patients
description	Food allergy carries high importance and responsibility, affecting an estimated 220 million people worldwide. It is a frequent cause of food-induced anaphylaxis, a life-threatening condition requiring a toll of about one death per 50 million people a year worldwide. In order to help patients to identify allergenic foods and thus avoid anaphylactic reactions, 66 countries over the 5 continents require by law that allergenic ingredients must be declared when used in prepackaged foods. Unfortunately, the mandatory allergen list is not uniform, but varies among different countries. The widespread adoption of Precautionary Allergen Labeling (PAL) results in a proliferation of unregulated PALs with different informative statements. In this situation, the need of a scientific consensus on the definition of food allergy and the identification of a tolerable risk with routinely used detection assays, considering not only the eliciting dose but also the food source, is urgent. The aim of this manuscript is: 1) to draw a picture of the global situation in terms of PALs, and 2) to highlight new approaches that could aid in tackling the problem of regulating the labeling of allergens. These include the Voluntary Incidental Trace Allergen Labelling (VITAL) system, which intersects reference doses and labelling decisions, and a direct quantification of trace amounts of allergens at lower limit of detection (LOD) levels in the food itself through proteomics. We here highlight how, although with some limitations, the steady advances in proteomic approaches possess higher sensitivity than the recommended VITAL reference doses, allowing the identification of allergens at much lower LOD levels than VITAL. Considering that each assay used to detect allergen in food products carries method-specific issues, a more comprehensive and harmonized approach implementing both quantitative and qualitative methods could help overcoming the risk stratification approach and the overuse of PALs, offering promise as the field moves forward towards improving consumers’ quality of life.
format	article
author	Alessandro Fiocchi, MD Davide Risso, PhD Audrey DunnGalvin, PhD Sandra N. González Díaz, MD, PhD Linda Monaci, PhD Vincenzo Fierro, MD Ignacio J. Ansotegui, MD, PhD
author_facet	Alessandro Fiocchi, MD Davide Risso, PhD Audrey DunnGalvin, PhD Sandra N. González Díaz, MD, PhD Linda Monaci, PhD Vincenzo Fierro, MD Ignacio J. Ansotegui, MD, PhD
author_sort	Alessandro Fiocchi, MD
title	Food labeling issues for severe food allergic patients
title_short	Food labeling issues for severe food allergic patients
title_full	Food labeling issues for severe food allergic patients
title_fullStr	Food labeling issues for severe food allergic patients
title_full_unstemmed	Food labeling issues for severe food allergic patients
title_sort	food labeling issues for severe food allergic patients
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/e2ddd10656a4408cb2a8cf2382a24961
work_keys_str_mv	AT alessandrofiocchimd foodlabelingissuesforseverefoodallergicpatients AT daviderissophd foodlabelingissuesforseverefoodallergicpatients AT audreydunngalvinphd foodlabelingissuesforseverefoodallergicpatients AT sandrangonzalezdiazmdphd foodlabelingissuesforseverefoodallergicpatients AT lindamonaciphd foodlabelingissuesforseverefoodallergicpatients AT vincenzofierromd foodlabelingissuesforseverefoodallergicpatients AT ignaciojansoteguimdphd foodlabelingissuesforseverefoodallergicpatients
_version_	1718431321988005888

Food labeling issues for severe food allergic patients

Ejemplares similares