Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan

Abstract The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability. Understanding the atomic interaction mechanism betw...

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Bibliographic Details
Main Authors: Jia-Wei Shen, Jiachen Li, Zhennan Zhao, Li Zhang, Guoteng Peng, Lijun Liang
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
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Online Access:https://doaj.org/article/e2e20c9f2b724f4aa32154b1f4b2a759
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