Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control
Abstract Obesity induces skeletal muscle dysfunction. The pathogenesis of which appears to substantially involve mitochondrial dysfunction, arising from impaired quality control. Exercise is a major therapeutic strategy against muscle dysfunction. Trimetazidine, a partial inhibitor of lipid oxidatio...
Saved in:
Main Authors: | Wenliang Zhang, Baiyang You, Dake Qi, Ling Qiu, Jeffrey W. Ripley-Gonzalez, Fan Zheng, Siqian Fu, Cui Li, Yaoshan Dun, Suixin Liu |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/e2f80afdf365485b81712d3ac7fe2b10 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Trimetazidine for prevention of induced ischemia and reperfusion of guinea pig retina
by: T Demir, et al.
Published: (2009) -
The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet
by: Leroy C. Joseph, et al.
Published: (2021) -
Suppression of High Fat Diet-Induced Liver Cell Injury by Swim Exercise
by: Dallak,Mohammad A.
Published: (2018) -
Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice
by: Jane M. Natividad, et al.
Published: (2018) -
Beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression
by: Liu MY, et al.
Published: (2018)