Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes
Germline mutations in homologous recombination (HR) DNA repair genes are linked to breast and ovarian cancer. Here, the authors show that mutually exclusive bi-allelic inactivation of HR genes are present in other cancer types and associated with genomic features of HR deficiency, expanding the pote...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/e31117fa0ba445099c2675a88b60cb9a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|