pH induced conformational alteration in human peroxiredoxin 6 might be responsible for its resistance against lysosomal pH or high temperature

Abstract Peroxiredoxin 6 (Prdx6), the ubiquitously expressed enzyme belonging to the family of peroxidases, namely, peroxiredoxins, exhibits a unique feature of functional compartmentalization within cells. Whereas, the enzyme localized in cytosol shows glutathione peroxidase activity, its lysosomal...

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Auteurs principaux: Rimpy Kaur Chowhan, Sunaina Hotumalani, Hamidur Rahaman, Laishram Rajendrakumar Singh
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/e31d544a68084e5db1f7144c130cd78b
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