Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant inf...

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Autores principales:	Emma J. Grant, Tracy M. Josephs, Liyen Loh, E. Bridie Clemens, Sneha Sant, Mandvi Bharadwaj, Weisan Chen, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3208577560a455ba744a1baab24971d
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spelling	oai:doaj.org-article:e3208577560a455ba744a1baab24971d2021-12-02T15:33:42ZBroad CD8+ T cell cross-recognition of distinct influenza A strains in humans10.1038/s41467-018-07815-52041-1723https://doaj.org/article/e3208577560a455ba744a1baab24971d2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07815-5https://doaj.org/toc/2041-1723Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant influenza epitope variants.Emma J. GrantTracy M. JosephsLiyen LohE. Bridie ClemensSneha SantMandvi BharadwajWeisan ChenJamie RossjohnStephanie GrasKatherine KedzierskaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emma J. Grant Tracy M. Josephs Liyen Loh E. Bridie Clemens Sneha Sant Mandvi Bharadwaj Weisan Chen Jamie Rossjohn Stephanie Gras Katherine Kedzierska Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
description	Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant influenza epitope variants.
format	article
author	Emma J. Grant Tracy M. Josephs Liyen Loh E. Bridie Clemens Sneha Sant Mandvi Bharadwaj Weisan Chen Jamie Rossjohn Stephanie Gras Katherine Kedzierska
author_facet	Emma J. Grant Tracy M. Josephs Liyen Loh E. Bridie Clemens Sneha Sant Mandvi Bharadwaj Weisan Chen Jamie Rossjohn Stephanie Gras Katherine Kedzierska
author_sort	Emma J. Grant
title	Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
title_short	Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
title_full	Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
title_fullStr	Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
title_full_unstemmed	Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
title_sort	broad cd8+ t cell cross-recognition of distinct influenza a strains in humans
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e3208577560a455ba744a1baab24971d
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Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

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