Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans
Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant inf...
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Nature Portfolio
2018
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oai:doaj.org-article:e3208577560a455ba744a1baab24971d2021-12-02T15:33:42ZBroad CD8+ T cell cross-recognition of distinct influenza A strains in humans10.1038/s41467-018-07815-52041-1723https://doaj.org/article/e3208577560a455ba744a1baab24971d2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07815-5https://doaj.org/toc/2041-1723Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant influenza epitope variants.Emma J. GrantTracy M. JosephsLiyen LohE. Bridie ClemensSneha SantMandvi BharadwajWeisan ChenJamie RossjohnStephanie GrasKatherine KedzierskaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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DOAJ |
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EN |
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Science Q |
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Science Q Emma J. Grant Tracy M. Josephs Liyen Loh E. Bridie Clemens Sneha Sant Mandvi Bharadwaj Weisan Chen Jamie Rossjohn Stephanie Gras Katherine Kedzierska Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans |
description |
Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant influenza epitope variants. |
format |
article |
author |
Emma J. Grant Tracy M. Josephs Liyen Loh E. Bridie Clemens Sneha Sant Mandvi Bharadwaj Weisan Chen Jamie Rossjohn Stephanie Gras Katherine Kedzierska |
author_facet |
Emma J. Grant Tracy M. Josephs Liyen Loh E. Bridie Clemens Sneha Sant Mandvi Bharadwaj Weisan Chen Jamie Rossjohn Stephanie Gras Katherine Kedzierska |
author_sort |
Emma J. Grant |
title |
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans |
title_short |
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans |
title_full |
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans |
title_fullStr |
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans |
title_full_unstemmed |
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans |
title_sort |
broad cd8+ t cell cross-recognition of distinct influenza a strains in humans |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/e3208577560a455ba744a1baab24971d |
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