Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Código QR

Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant inf...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Emma J. Grant, Tracy M. Josephs, Liyen Loh, E. Bridie Clemens, Sneha Sant, Mandvi Bharadwaj, Weisan Chen, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3208577560a455ba744a1baab24971d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide
por: Kok Fei Chan, et al.
Publicado: (2018)

Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients
por: Thi H. O. Nguyen, et al.
Publicado: (2021)

Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph
por: C. E. van de Sandt, et al.
Publicado: (2019)

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
por: Luca Hensen, et al.
Publicado: (2021)

Epitope-targeting platform for broadly protective influenza vaccines.
por: David F Zeigler, et al.
Publicado: (2021)

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids
por: Adam Shahine, et al.
Publicado: (2019)

MAIT cells contribute to protection against lethal influenza infection in vivo
por: Bonnie van Wilgenburg, et al.
Publicado: (2018)

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
por: Stephanie Gras, et al.
Publicado: (2016)

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies
por: Christopher A. Cottrell, et al.
Publicado: (2021)

Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
por: Nikolas Friedrich, et al.
Publicado: (2021)

In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity
por: Nicholas C. Wu, et al.
Publicado: (2017)

Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies
por: Rachael Keating, et al.
Publicado: (2020)

Nonreplicating Influenza A Virus Vaccines Confer Broad Protection against Lethal Challenge
por: Mariana Baz, et al.
Publicado: (2015)

A Host-Restricted Self-Attenuated Influenza Virus Provides Broad Pan-Influenza A Protection in a Mouse Model
por: Minjin Kim, et al.
Publicado: (2021)

Bacterial protease uses distinct thermodynamic signatures for substrate recognition
por: Gustavo Arruda Bezerra, et al.
Publicado: (2017)

Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens
por: Jérôme Le Nours, et al.
Publicado: (2016)

A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action
por: Ning Chai, et al.
Publicado: (2017)

Gene expression signature-based screening identifies new broadly effective influenza a antivirals.
por: Laurence Josset, et al.
Publicado: (2010)

Sublingual immunization with M2-based vaccine induces broad protective immunity against influenza.
por: Byoung-Shik Shim, et al.
Publicado: (2011)

Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses
por: Lei Deng, et al.
Publicado: (2018)

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition
por: Gautham R. Balaji, et al.
Publicado: (2018)

Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition
por: Pooja Kumari, et al.
Publicado: (2018)

Detection of Evolutionarily Distinct Avian Influenza A Viruses in Antarctica
por: Aeron C. Hurt, et al.
Publicado: (2014)

Plastid phylogenomics with broad taxon sampling further elucidates the distinct evolutionary origins and timing of secondary green plastids
por: Christopher Jackson, et al.
Publicado: (2018)

A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells.
por: Yi-An Ko, et al.
Publicado: (2021)

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice
por: Wenqian He, et al.
Publicado: (2017)

A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection
por: Yansheng Li, et al.
Publicado: (2021)

Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection
por: M. Muenchhoff, et al.
Publicado: (2020)

Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
por: Brianna L. Bullard, et al.
Publicado: (2021)

Influenza Virus Infection Induces a Narrow Antibody Response in Children but a Broad Recall Response in Adults
por: Philip Meade, et al.
Publicado: (2020)

Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells
por: Michael S. Piepenbrink, et al.
Publicado: (2019)

An Intranasal Virus-Like Particle Vaccine Broadly Protects Mice from Multiple Subtypes of Influenza A Virus
por: Louis M. Schwartzman, et al.
Publicado: (2015)

Correction: Corrigendum: A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action
por: Ning Chai, et al.
Publicado: (2017)

How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin
por: Michael B. Doud, et al.
Publicado: (2018)

Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
por: Sophie A Valkenburg, et al.
Publicado: (2010)

Multiple-clade H5N1 influenza split vaccine elicits broad cross protection against lethal influenza virus challenge in mice by intranasal vaccination.
por: Penghui Yang, et al.
Publicado: (2012)

Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection.
por: Lukasz Kedzierski, et al.
Publicado: (2014)

A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific memory B cells to evolve
por: Ying Fu, et al.
Publicado: (2016)

Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice
por: Teddy John Wohlbold, et al.
Publicado: (2015)

Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans
por: Daniel Stadlbauer, et al.
Publicado: (2017)