Safety and efficacy of combination of suberoylamilide hydroxyamic acid and mitomycin C in reducing pro-fibrotic changes in human corneal epithelial cells

Safety and efficacy of combination of suberoylamilide hydroxyamic acid and mitomycin C in reducing pro-fibrotic changes in human corneal epithelial cells

Abstract Corneal haze post refractive surgery is prevented by mitomycin c (MMC) treatment though it can lead to corneal endothelial damage, persistent epithelial defects and necrosis of cells. Suberanilohydroxamic acid (SAHA) however has been proposed to prevent corneal haze without any adverse effe...

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Bibliographic Details
Main Authors: Rohit Shetty, Nimisha Rajiv Kumar, Murali Subramani, Lekshmi Krishna, Ponnalagu Murugeswari, Himanshu Matalia, Pooja Khamar, Zelda V. Dadachanji, Rajiv R. Mohan, Arkasubhra Ghosh, Debashish Das
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e342de859592401f9fa932eecd3fc8a5
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https://doaj.org/article/e342de859592401f9fa932eecd3fc8a5

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