Cancer-Associated Fibroblasts Promote the Upregulation of PD-L1 Expression Through Akt Phosphorylation in Colorectal Cancer

Upregulation of immune checkpoint proteins is one of the main mechanisms for tumor immune escape. The expression of programmed death ligand-1 (PD-L1) in colorectal cancer (CRC) is higher than in normal colorectal epithelial tissue, and patients with higher PD-L1 expression have a poorer prognosis. A...

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Auteurs principaux: Yang Gao, Zhao Sun, Junjie Gu, Zhe Li, Xiuxiu Xu, Chunling Xue, Xuechun Li, Lin Zhao, Jianfeng Zhou, Chunmei Bai, Qin Han, Robert Chunhua Zhao
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/e34b2dc6c5254c04845e543dc93fbe09
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