GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
GATA3 has been considered to be primarily associated with CD4+ Th2 cell function. Using CD4+ effector memory that re-express CD45RA (EMRA) T cells the authors show that in response to DNA damage GATA3 can regulate increase of mitochondrial mass and biogenesis involving AMPK.
Guardado en:
Autores principales: | Lauren A. Callender, Johannes Schroth, Elizabeth C. Carroll, Conor Garrod-Ketchley, Lisa E. L. Romano, Eleanor Hendy, Audrey Kelly, Paul Lavender, Arne N. Akbar, J. Paul Chapple, Sian M. Henson |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e3707e322df34c44b2251936c03964a1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The Role of Exercise and Mitochondrial Biogenesis in Aging Process
por: Taufiqurrachman Nasihun
Publicado: (2018) -
Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults
por: Koichi Hasegawa, et al.
Publicado: (2016) -
Chronic Activation of AMPK Induces Mitochondrial Biogenesis through Differential Phosphorylation and Abundance of Mitochondrial Proteins in <i>Dictyostelium discoideum</i>
por: Malgorzata Heidorn-Czarna, et al.
Publicado: (2021) -
Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol
por: Robert B. Cameron, et al.
Publicado: (2017) -
Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes
por: Isao Masuda, et al.
Publicado: (2018)