Asymmetric assembly of high-value α-functionalized organic acids using a biocatalytic chiral-group-resetting process
Alpha-functionalized organic acids are building blocks of many bioactive compounds. Here, the authors developed a toolbox-like, modular set of enzymes that reset chiral groups, turning achiral glycine and simple aldehydes into stereodefined α-keto acids, α-hydroxy acids, and α-amino acids.
Enregistré dans:
Auteurs principaux: | , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/e395fb7be3ba460d9ae480a09a69c7a8 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|