Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
Influenza infection during pregnancy can affect health of offspring but it is not clear how this affects immune responses. Here the authors use a mouse model to show that influenza infection during pregnancy can increase susceptibility to secondary infection and alter immune cell function in offspri...
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Nature Portfolio
2021
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oai:doaj.org-article:e3a6daa33a83457bb051d8afd208dbb62021-12-02T17:08:39ZOffspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life10.1038/s41467-021-25220-32041-1723https://doaj.org/article/e3a6daa33a83457bb051d8afd208dbb62021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25220-3https://doaj.org/toc/2041-1723Influenza infection during pregnancy can affect health of offspring but it is not clear how this affects immune responses. Here the authors use a mouse model to show that influenza infection during pregnancy can increase susceptibility to secondary infection and alter immune cell function in offspring.Henning JacobsenKerstin Walendy-GnirßNilgün Tekin-BubenheimNancy Mounogou KouassiIsabel Ben-BatallaNikolaus BerenbrokMartin WolffVinicius Pinho dos ReisMartin ZicklerLucas SchollAnnette GriesHanna JaniaAndreas KloetgenArne DüsedauGundula Pilnitz-StolzeAicha JeridiAli Önder YildirimHelmut FuchsValerie Gailus-DurnerClaudia StoegerMartin Hrabe de AngelisTatjana ManuylovaKarin KlingelFiona J. CulleyJochen BehrendsSonja LogesBianca SchneiderSusanne Krauss-EtschmannPeter OpenshawGülsah GabrielNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Henning Jacobsen Kerstin Walendy-Gnirß Nilgün Tekin-Bubenheim Nancy Mounogou Kouassi Isabel Ben-Batalla Nikolaus Berenbrok Martin Wolff Vinicius Pinho dos Reis Martin Zickler Lucas Scholl Annette Gries Hanna Jania Andreas Kloetgen Arne Düsedau Gundula Pilnitz-Stolze Aicha Jeridi Ali Önder Yildirim Helmut Fuchs Valerie Gailus-Durner Claudia Stoeger Martin Hrabe de Angelis Tatjana Manuylova Karin Klingel Fiona J. Culley Jochen Behrends Sonja Loges Bianca Schneider Susanne Krauss-Etschmann Peter Openshaw Gülsah Gabriel Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
description |
Influenza infection during pregnancy can affect health of offspring but it is not clear how this affects immune responses. Here the authors use a mouse model to show that influenza infection during pregnancy can increase susceptibility to secondary infection and alter immune cell function in offspring. |
format |
article |
author |
Henning Jacobsen Kerstin Walendy-Gnirß Nilgün Tekin-Bubenheim Nancy Mounogou Kouassi Isabel Ben-Batalla Nikolaus Berenbrok Martin Wolff Vinicius Pinho dos Reis Martin Zickler Lucas Scholl Annette Gries Hanna Jania Andreas Kloetgen Arne Düsedau Gundula Pilnitz-Stolze Aicha Jeridi Ali Önder Yildirim Helmut Fuchs Valerie Gailus-Durner Claudia Stoeger Martin Hrabe de Angelis Tatjana Manuylova Karin Klingel Fiona J. Culley Jochen Behrends Sonja Loges Bianca Schneider Susanne Krauss-Etschmann Peter Openshaw Gülsah Gabriel |
author_facet |
Henning Jacobsen Kerstin Walendy-Gnirß Nilgün Tekin-Bubenheim Nancy Mounogou Kouassi Isabel Ben-Batalla Nikolaus Berenbrok Martin Wolff Vinicius Pinho dos Reis Martin Zickler Lucas Scholl Annette Gries Hanna Jania Andreas Kloetgen Arne Düsedau Gundula Pilnitz-Stolze Aicha Jeridi Ali Önder Yildirim Helmut Fuchs Valerie Gailus-Durner Claudia Stoeger Martin Hrabe de Angelis Tatjana Manuylova Karin Klingel Fiona J. Culley Jochen Behrends Sonja Loges Bianca Schneider Susanne Krauss-Etschmann Peter Openshaw Gülsah Gabriel |
author_sort |
Henning Jacobsen |
title |
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
title_short |
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
title_full |
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
title_fullStr |
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
title_full_unstemmed |
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
title_sort |
offspring born to influenza a virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/e3a6daa33a83457bb051d8afd208dbb6 |
work_keys_str_mv |
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