Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

Influenza infection during pregnancy can affect health of offspring but it is not clear how this affects immune responses. Here the authors use a mouse model to show that influenza infection during pregnancy can increase susceptibility to secondary infection and alter immune cell function in offspri...

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Autores principales: Henning Jacobsen, Kerstin Walendy-Gnirß, Nilgün Tekin-Bubenheim, Nancy Mounogou Kouassi, Isabel Ben-Batalla, Nikolaus Berenbrok, Martin Wolff, Vinicius Pinho dos Reis, Martin Zickler, Lucas Scholl, Annette Gries, Hanna Jania, Andreas Kloetgen, Arne Düsedau, Gundula Pilnitz-Stolze, Aicha Jeridi, Ali Önder Yildirim, Helmut Fuchs, Valerie Gailus-Durner, Claudia Stoeger, Martin Hrabe de Angelis, Tatjana Manuylova, Karin Klingel, Fiona J. Culley, Jochen Behrends, Sonja Loges, Bianca Schneider, Susanne Krauss-Etschmann, Peter Openshaw, Gülsah Gabriel
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e3a6daa33a83457bb051d8afd208dbb6
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spelling oai:doaj.org-article:e3a6daa33a83457bb051d8afd208dbb62021-12-02T17:08:39ZOffspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life10.1038/s41467-021-25220-32041-1723https://doaj.org/article/e3a6daa33a83457bb051d8afd208dbb62021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25220-3https://doaj.org/toc/2041-1723Influenza infection during pregnancy can affect health of offspring but it is not clear how this affects immune responses. Here the authors use a mouse model to show that influenza infection during pregnancy can increase susceptibility to secondary infection and alter immune cell function in offspring.Henning JacobsenKerstin Walendy-GnirßNilgün Tekin-BubenheimNancy Mounogou KouassiIsabel Ben-BatallaNikolaus BerenbrokMartin WolffVinicius Pinho dos ReisMartin ZicklerLucas SchollAnnette GriesHanna JaniaAndreas KloetgenArne DüsedauGundula Pilnitz-StolzeAicha JeridiAli Önder YildirimHelmut FuchsValerie Gailus-DurnerClaudia StoegerMartin Hrabe de AngelisTatjana ManuylovaKarin KlingelFiona J. CulleyJochen BehrendsSonja LogesBianca SchneiderSusanne Krauss-EtschmannPeter OpenshawGülsah GabrielNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Henning Jacobsen
Kerstin Walendy-Gnirß
Nilgün Tekin-Bubenheim
Nancy Mounogou Kouassi
Isabel Ben-Batalla
Nikolaus Berenbrok
Martin Wolff
Vinicius Pinho dos Reis
Martin Zickler
Lucas Scholl
Annette Gries
Hanna Jania
Andreas Kloetgen
Arne Düsedau
Gundula Pilnitz-Stolze
Aicha Jeridi
Ali Önder Yildirim
Helmut Fuchs
Valerie Gailus-Durner
Claudia Stoeger
Martin Hrabe de Angelis
Tatjana Manuylova
Karin Klingel
Fiona J. Culley
Jochen Behrends
Sonja Loges
Bianca Schneider
Susanne Krauss-Etschmann
Peter Openshaw
Gülsah Gabriel
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
description Influenza infection during pregnancy can affect health of offspring but it is not clear how this affects immune responses. Here the authors use a mouse model to show that influenza infection during pregnancy can increase susceptibility to secondary infection and alter immune cell function in offspring.
format article
author Henning Jacobsen
Kerstin Walendy-Gnirß
Nilgün Tekin-Bubenheim
Nancy Mounogou Kouassi
Isabel Ben-Batalla
Nikolaus Berenbrok
Martin Wolff
Vinicius Pinho dos Reis
Martin Zickler
Lucas Scholl
Annette Gries
Hanna Jania
Andreas Kloetgen
Arne Düsedau
Gundula Pilnitz-Stolze
Aicha Jeridi
Ali Önder Yildirim
Helmut Fuchs
Valerie Gailus-Durner
Claudia Stoeger
Martin Hrabe de Angelis
Tatjana Manuylova
Karin Klingel
Fiona J. Culley
Jochen Behrends
Sonja Loges
Bianca Schneider
Susanne Krauss-Etschmann
Peter Openshaw
Gülsah Gabriel
author_facet Henning Jacobsen
Kerstin Walendy-Gnirß
Nilgün Tekin-Bubenheim
Nancy Mounogou Kouassi
Isabel Ben-Batalla
Nikolaus Berenbrok
Martin Wolff
Vinicius Pinho dos Reis
Martin Zickler
Lucas Scholl
Annette Gries
Hanna Jania
Andreas Kloetgen
Arne Düsedau
Gundula Pilnitz-Stolze
Aicha Jeridi
Ali Önder Yildirim
Helmut Fuchs
Valerie Gailus-Durner
Claudia Stoeger
Martin Hrabe de Angelis
Tatjana Manuylova
Karin Klingel
Fiona J. Culley
Jochen Behrends
Sonja Loges
Bianca Schneider
Susanne Krauss-Etschmann
Peter Openshaw
Gülsah Gabriel
author_sort Henning Jacobsen
title Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
title_short Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
title_full Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
title_fullStr Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
title_full_unstemmed Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
title_sort offspring born to influenza a virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e3a6daa33a83457bb051d8afd208dbb6
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