In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.

por Ingeborg Klymiuk, Lukas Kenner, Thure Adler, Dirk H Busch, Auke Boersma, Martin Irmler, Barbara Fridrich, Valérie Gailus-Durner, Helmut Fuchs, Nicole Leitner, Mathias Müller, Ralf Kühn, Michaela Schlederer, Irina Treise, Martin Hrabě de Angelis, Johannes Beckers
Publicado 2012

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression

por Aimilios Kaklamanos, Jan Rozman, Manolis Roulis, Niki Karagianni, Maria Armaka, Moya Wu, Laura Brachthäuser, Julia Calzada-Wack, Marion Horsch, Johannes Beckers, Birgit Rathkolb, Thure Adler, Frauke Neff, Eckhard Wolf, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabe de Angelis, George Kollias
Publicado 2017

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification

por Maria C. Ferreira dos Santos, Cole P. Anderson, Susanne Neschen, Kimberly B. Zumbrennen-Bullough, Steven J. Romney, Melanie Kahle-Stephan, Birgit Rathkolb, Valerie Gailus-Durner, Helmut Fuchs, Eckhard Wolf, Jan Rozman, Martin Hrabe de Angelis, Weiling Maggie Cai, Malini Rajan, Jennifer Hu, Peter C. Dedon, Elizabeth A. Leibold
Publicado 2020

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

por Christoph Kleinschnitz, Henrike Grund, Kirstin Wingler, Melanie E Armitage, Emma Jones, Manish Mittal, David Barit, Tobias Schwarz, Christian Geis, Peter Kraft, Konstanze Barthel, Michael K Schuhmann, Alexander M Herrmann, Sven G Meuth, Guido Stoll, Sabine Meurer, Anja Schrewe, Lore Becker, Valérie Gailus-Durner, Helmut Fuchs, Thomas Klopstock, Martin Hrabé de Angelis, Karin Jandeleit-Dahm, Ajay M Shah, Norbert Weissmann, Harald H H W Schmidt
Publicado 2010

A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.

por Sabine M Hölter, Mary Stromberg, Marina Kovalenko, Lillian Garrett, Lisa Glasl, Edith Lopez, Jolene Guide, Alexander Götz, Wolfgang Hans, Lore Becker, Birgit Rathkolb, Jan Rozman, Anja Schrewed, Martin Klingenspor, Thomas Klopstock, Holger Schulz, Eckhard Wolf, Wolfgang Wursta, Tammy Gillis, Hiroko Wakimoto, Jonathan Seidman, Marcy E MacDonald, Susan Cotman, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Jong-Min Lee, Vanessa C Wheeler
Publicado 2013

Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

por Henning Jacobsen, Kerstin Walendy-Gnirß, Nilgün Tekin-Bubenheim, Nancy Mounogou Kouassi, Isabel Ben-Batalla, Nikolaus Berenbrok, Martin Wolff, Vinicius Pinho dos Reis, Martin Zickler, Lucas Scholl, Annette Gries, Hanna Jania, Andreas Kloetgen, Arne Düsedau, Gundula Pilnitz-Stolze, Aicha Jeridi, Ali Önder Yildirim, Helmut Fuchs, Valerie Gailus-Durner, Claudia Stoeger, Martin Hrabe de Angelis, Tatjana Manuylova, Karin Klingel, Fiona J. Culley, Jochen Behrends, Sonja Loges, Bianca Schneider, Susanne Krauss-Etschmann, Peter Openshaw, Gülsah Gabriel
Publicado 2021

Pleiotropic functions for transcription factor zscan10.

por Petra Kraus, Sivakamasundari V, Hong Bing Yu, Xing Xing, Siew Lan Lim, Thure Adler, Juan Antonio Aguilar Pimentel, Lore Becker, Alexander Bohla, Lillian Garrett, Wolfgang Hans, Sabine M Hölter, Eva Janas, Kristin Moreth, Cornelia Prehn, Oliver Puk, Birgit Rathkolb, Jan Rozman, Jerzy Adamski, Raffi Bekeredjian, Dirk H Busch, Jochen Graw, Martin Klingenspor, Thomas Klopstock, Frauke Neff, Markus Ollert, Tobias Stoeger, Ali Önder Yildrim, Oliver Eickelberg, Eckhard Wolf, Wolfgang Wurst, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Thomas Lufkin, Lawrence W Stanton
Publicado 2014

Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice

por Kan Xie, Frauke Neff, Astrid Markert, Jan Rozman, Juan Antonio Aguilar-Pimentel, Oana Veronica Amarie, Lore Becker, Robert Brommage, Lillian Garrett, Kristin S. Henzel, Sabine M. Hölter, Dirk Janik, Isabelle Lehmann, Kristin Moreth, Brandon L. Pearson, Ildiko Racz, Birgit Rathkolb, Devon P. Ryan, Susanne Schröder, Irina Treise, Raffi Bekeredjian, Dirk H. Busch, Jochen Graw, Gerhard Ehninger, Martin Klingenspor, Thomas Klopstock, Markus Ollert, Michael Sandholzer, Carsten Schmidt-Weber, Marco Weiergräber, Eckhard Wolf, Wolfgang Wurst, Andreas Zimmer, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Dan Ehninger
Publicado 2017

Human and mouse essentiality screens as a resource for disease gene discovery

por Pilar Cacheiro, Violeta Muñoz-Fuentes, Stephen A. Murray, Mary E. Dickinson, Maja Bucan, Lauryl M. J. Nutter, Kevin A. Peterson, Hamed Haselimashhadi, Ann M. Flenniken, Hugh Morgan, Henrik Westerberg, Tomasz Konopka, Chih-Wei Hsu, Audrey Christiansen, Denise G. Lanza, Arthur L. Beaudet, Jason D. Heaney, Helmut Fuchs, Valerie Gailus-Durner, Tania Sorg, Jan Prochazka, Vendula Novosadova, Christopher J. Lelliott, Hannah Wardle-Jones, Sara Wells, Lydia Teboul, Heather Cater, Michelle Stewart, Tertius Hough, Wolfgang Wurst, Radislav Sedlacek, David J. Adams, John R. Seavitt, Glauco Tocchini-Valentini, Fabio Mammano, Robert E. Braun, Colin McKerlie, Yann Herault, Martin Hrabě de Angelis, Ann-Marie Mallon, K. C.  Kent Lloyd, Steve D. M. Brown, Helen Parkinson, Terrence F. Meehan, Damian Smedley, The Genomics England Research Consortium, The International Mouse Phenotyping Consortium
Publicado 2020

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

por Jan Rozman, Birgit Rathkolb, Manuela A. Oestereicher, Christine Schütt, Aakash Chavan Ravindranath, Stefanie Leuchtenberger, Sapna Sharma, Martin Kistler, Monja Willershäuser, Robert Brommage, Terrence F. Meehan, Jeremy Mason, Hamed Haselimashhadi, IMPC Consortium, Tertius Hough, Ann-Marie Mallon, Sara Wells, Luis Santos, Christopher J. Lelliott, Jacqueline K. White, Tania Sorg, Marie-France Champy, Lynette R. Bower, Corey L. Reynolds, Ann M. Flenniken, Stephen A. Murray, Lauryl M. J. Nutter, Karen L. Svenson, David West, Glauco P. Tocchini-Valentini, Arthur L. Beaudet, Fatima Bosch, Robert B. Braun, Michael S. Dobbie, Xiang Gao, Yann Herault, Ala Moshiri, Bret A. Moore, K. C. Kent Lloyd, Colin McKerlie, Hiroshi Masuya, Nobuhiko Tanaka, Paul Flicek, Helen E. Parkinson, Radislav Sedlacek, Je Kyung Seong, Chi-Kuang Leo Wang, Mark Moore, Steve D. Brown, Matthias H. Tschöp, Wolfgang Wurst, Martin Klingenspor, Eckhard Wolf, Johannes Beckers, Fausto Machicao, Andreas Peter, Harald Staiger, Hans-Ulrich Häring, Harald Grallert, Monica Campillos, Holger Maier, Helmut Fuchs, Valerie Gailus-Durner, Thomas Werner, Martin Hrabe de Angelis
Publicado 2018