Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Código QR

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Abstract Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial b...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hanna Ungewiß, Franziska Vielmuth, Shintaro T. Suzuki, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Daniela Kugelmann, Nicolas Schlegel, Jens Waschke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e3bf6cdb8c36482bbd4222776e21ef8f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition
por: Takaya Handa, et al.
Publicado: (2021)

The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis.
por: Ralf Müller, et al.
Publicado: (2013)

Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase.
por: Hye-Ryung Choi, et al.
Publicado: (2013)

TMPYP4 exerted antitumor effects in human cervical cancer cells through activation of p38 mitogen-activated protein kinase
por: Cheng,Ming‑Jun, et al.
Publicado: (2017)

Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells
por: Sabine Bernegger, et al.
Publicado: (2021)

Evolutionary history of the vertebrate mitogen activated protein kinases family.
por: Meng Li, et al.
Publicado: (2011)

Multi-Target In Silico Prediction of Inhibitors for Mitogen-Activated Protein Kinase-Interacting Kinases
por: Amit Kumar Halder, et al.
Publicado: (2021)

Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum
por: Christopher A. Blackwood, et al.
Publicado: (2021)

In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
por: Abhirup Paul, et al.
Publicado: (2021)

In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis
por: Abhirup Paul, et al.
Publicado: (2021)

Revealing the suppressive role of protein kinase C delta and p38 mitogen-activated protein kinase (MAPK)/NF-κB axis associates with lenvatinib-inhibited progression in hepatocellular carcinoma in vitro and in vivo
por: Ching-Hsuan Wu, et al.
Publicado: (2022)

Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice.
por: Katharina Boch, et al.
Publicado: (2021)

Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice
por: Katharina Boch, et al.
Publicado: (2021)

Mechanical loading of desmosomes depends on the magnitude and orientation of external stress
por: Andrew J. Price, et al.
Publicado: (2018)

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
por: Debora Bogani, et al.
Publicado: (2009)

Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils.
por: Mandy E Burnham, et al.
Publicado: (2014)

Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart
por: Hoda Moazzen, et al.
Publicado: (2021)

MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease: Running Title: Role of miR-191-5p in Alzheimer’s disease
por: Wenjun Wan, et al.
Publicado: (2021)

EFFECTS OF STATINS AND OTHER BIOLOGICAL PREPARATIONS UPON ACTIVATION OF MITOGEN-ACTIVATED PROTEIN KINASES IN PATIENTS WITH RHEUMATOID ARTHRITIS
por: I. V. Shirinsky, et al.
Publicado: (2014)

Squamous cell carcinoma of the soft palate associated with autoantibodies to desmoglein 1 and 3
por: Yoshifumi Maumi, et al.
Publicado: (2013)

IgA pemphigus showing IgA antibodies to desmoglein 1 and 3
por: Salama Hegazy, et al.
Publicado: (2016)

Acetylcorynoline impairs the maturation of mouse bone marrow-derived dendritic cells via suppression of IκB kinase and mitogen-activated protein kinase activities.
por: Ru-Huei Fu, et al.
Publicado: (2013)

High mitogenic stimulation arrests angiogenesis
por: Samuel Pontes-Quero, et al.
Publicado: (2019)

The proteasome inhibitor bortezomib enhances ATRA-induced differentiation of neuroblastoma cells via the JNK mitogen-activated protein kinase pathway.
por: Peihua Luo, et al.
Publicado: (2011)

Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis
por: Hanna Niehues, et al.
Publicado: (2022)

Proliferation-stimulating effect of colony stimulating factor 2 on porcine trophectoderm cells is mediated by activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase.
por: Wooyoung Jeong, et al.
Publicado: (2014)

In vitro functional analyses of arrhythmogenic right ventricular cardiomyopathy-associated desmoglein-2-missense variations.
por: Anna Gaertner, et al.
Publicado: (2012)

Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase.
por: Matthäus Getlik, et al.
Publicado: (2012)

Identification of the elementary structural units of the DNA damage response
por: Francesco Natale, et al.
Publicado: (2017)

Kinome-Wide RNA Interference Screening Identifies Mitogen-Activated Protein Kinases and Phosphatidylinositol Metabolism as Key Factors for Rabies Virus Infection
por: Benoit Besson, et al.
Publicado: (2019)

Publisher Correction: High mitogenic stimulation arrests angiogenesis
por: Samuel Pontes-Quero, et al.
Publicado: (2019)

Epithelial p38alpha controls immune cell recruitment in the colonic mucosa.
por: Young Jun Kang, et al.
Publicado: (2010)

CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement
por: Emilie Vassal-Stermann, et al.
Publicado: (2019)

Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.
por: Betti Giusti, et al.
Publicado: (2013)

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
por: Zachary J. Reitman, et al.
Publicado: (2019)

Staphylococcal LTA antagonizes the B cell-mitogenic potential of LPS
por: Seok-Seong Kang, et al.
Publicado: (2018)

Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus
por: Elias Walter, et al.
Publicado: (2017)

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs
por: Carmen Herrero-de-Dios, et al.
Publicado: (2018)

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
por: Adriana Oliveira Manfiolli, et al.
Publicado: (2019)

Inhibitory Effect of Phellinus baumii Extract on CFA-Induced Inflammation in MH-S Cells through Nuclear Factor-κB and Mitogen-Activated Protein Kinase Signaling Pathways
por: H. M. Arif Ullah, et al.
Publicado: (2021)