Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

QR Code

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Abstract Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial b...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Hanna Ungewiß, Franziska Vielmuth, Shintaro T. Suzuki, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Daniela Kugelmann, Nicolas Schlegel, Jens Waschke
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/e3bf6cdb8c36482bbd4222776e21ef8f
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition
par: Takaya Handa, et autres
Publié: (2021)

The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis.
par: Ralf Müller, et autres
Publié: (2013)

Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase.
par: Hye-Ryung Choi, et autres
Publié: (2013)

TMPYP4 exerted antitumor effects in human cervical cancer cells through activation of p38 mitogen-activated protein kinase
par: Cheng,Ming‑Jun, et autres
Publié: (2017)

Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells
par: Sabine Bernegger, et autres
Publié: (2021)

Evolutionary history of the vertebrate mitogen activated protein kinases family.
par: Meng Li, et autres
Publié: (2011)

Multi-Target In Silico Prediction of Inhibitors for Mitogen-Activated Protein Kinase-Interacting Kinases
par: Amit Kumar Halder, et autres
Publié: (2021)

Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum
par: Christopher A. Blackwood, et autres
Publié: (2021)

In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis.
par: Abhirup Paul, et autres
Publié: (2021)

In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis
par: Abhirup Paul, et autres
Publié: (2021)

Revealing the suppressive role of protein kinase C delta and p38 mitogen-activated protein kinase (MAPK)/NF-κB axis associates with lenvatinib-inhibited progression in hepatocellular carcinoma in vitro and in vivo
par: Ching-Hsuan Wu, et autres
Publié: (2022)

Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice.
par: Katharina Boch, et autres
Publié: (2021)

Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice
par: Katharina Boch, et autres
Publié: (2021)

Mechanical loading of desmosomes depends on the magnitude and orientation of external stress
par: Andrew J. Price, et autres
Publié: (2018)

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
par: Debora Bogani, et autres
Publié: (2009)

Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils.
par: Mandy E Burnham, et autres
Publié: (2014)

Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart
par: Hoda Moazzen, et autres
Publié: (2021)

MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease: Running Title: Role of miR-191-5p in Alzheimer’s disease
par: Wenjun Wan, et autres
Publié: (2021)

EFFECTS OF STATINS AND OTHER BIOLOGICAL PREPARATIONS UPON ACTIVATION OF MITOGEN-ACTIVATED PROTEIN KINASES IN PATIENTS WITH RHEUMATOID ARTHRITIS
par: I. V. Shirinsky, et autres
Publié: (2014)

Squamous cell carcinoma of the soft palate associated with autoantibodies to desmoglein 1 and 3
par: Yoshifumi Maumi, et autres
Publié: (2013)

IgA pemphigus showing IgA antibodies to desmoglein 1 and 3
par: Salama Hegazy, et autres
Publié: (2016)

Acetylcorynoline impairs the maturation of mouse bone marrow-derived dendritic cells via suppression of IκB kinase and mitogen-activated protein kinase activities.
par: Ru-Huei Fu, et autres
Publié: (2013)

High mitogenic stimulation arrests angiogenesis
par: Samuel Pontes-Quero, et autres
Publié: (2019)

The proteasome inhibitor bortezomib enhances ATRA-induced differentiation of neuroblastoma cells via the JNK mitogen-activated protein kinase pathway.
par: Peihua Luo, et autres
Publié: (2011)

Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis
par: Hanna Niehues, et autres
Publié: (2022)

Proliferation-stimulating effect of colony stimulating factor 2 on porcine trophectoderm cells is mediated by activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase.
par: Wooyoung Jeong, et autres
Publié: (2014)

In vitro functional analyses of arrhythmogenic right ventricular cardiomyopathy-associated desmoglein-2-missense variations.
par: Anna Gaertner, et autres
Publié: (2012)

Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase.
par: Matthäus Getlik, et autres
Publié: (2012)

Identification of the elementary structural units of the DNA damage response
par: Francesco Natale, et autres
Publié: (2017)

Kinome-Wide RNA Interference Screening Identifies Mitogen-Activated Protein Kinases and Phosphatidylinositol Metabolism as Key Factors for Rabies Virus Infection
par: Benoit Besson, et autres
Publié: (2019)

Publisher Correction: High mitogenic stimulation arrests angiogenesis
par: Samuel Pontes-Quero, et autres
Publié: (2019)

Epithelial p38alpha controls immune cell recruitment in the colonic mucosa.
par: Young Jun Kang, et autres
Publié: (2010)

CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement
par: Emilie Vassal-Stermann, et autres
Publié: (2019)

Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.
par: Betti Giusti, et autres
Publié: (2013)

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
par: Zachary J. Reitman, et autres
Publié: (2019)

Staphylococcal LTA antagonizes the B cell-mitogenic potential of LPS
par: Seok-Seong Kang, et autres
Publié: (2018)

Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus
par: Elias Walter, et autres
Publié: (2017)

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs
par: Carmen Herrero-de-Dios, et autres
Publié: (2018)

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
par: Adriana Oliveira Manfiolli, et autres
Publié: (2019)

Inhibitory Effect of Phellinus baumii Extract on CFA-Induced Inflammation in MH-S Cells through Nuclear Factor-κB and Mitogen-Activated Protein Kinase Signaling Pathways
par: H. M. Arif Ullah, et autres
Publié: (2021)