Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children

Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children

Abstract Pediatric tuberculosis (TB) is challenging to diagnose, confirmed by growth of Mycobacterium tuberculosis at best in 40% of cases. The WHO has assigned high priority to the development of non-sputum diagnostic tools. We therefore sought to identify transcriptional signatures in whole blood...

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Main Authors: John Espen Gjøen, Synne Jenum, Dhanasekaran Sivakumaran, Aparna Mukherjee, Ragini Macaden, Sushil K. Kabra, Rakesh Lodha, Tom H. M. Ottenhoff, Marielle C. Haks, Timothy Mark Doherty, Christian Ritz, Harleen M. S. Grewal
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e3c7dd1d08254a8dbb04f27f1e98da63
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