Detection of EGFR mutation in plasma using multiplex allele-specific PCR (MAS-PCR) and surface enhanced Raman spectroscopy

Abstract In this study, surface enhanced Raman spectroscopy (SERS) in combination with multiplexed polymerase chain reaction (PCR) was utilized to detect mutations of exons 19 and 21 of the epidermal growth factor receptor (EGFR) gene. Through the use of multiplexed PCR, the two mutation types were...

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Bibliographic Details
Main Authors: Xiaozhou Li, Tianyue Yang, Caesar Siqi Li, Deli Wang, Youtao Song, Lili Jin
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/e3dd0c1ae82446f2aade50835824509f
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