Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies

Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies

Unrecognized progenitor cell perturbations underlying a disease state may limit the efficacy of cell therapies. Here, the authors use high-throughput, single-cell transcriptional analysis to identify disease-specific cellular alterations and prospectively isolate restorative cell subpopulations.

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Bibliographic Details
Main Authors: Robert C. Rennert, Michael Januszyk, Michael Sorkin, Melanie Rodrigues, Zeshaan N. Maan, Dominik Duscher, Alexander J. Whittam, Revanth Kosaraju, Michael T. Chung, Kevin Paik, Alexander Y. Li, Michael Findlay, Jason P. Glotzbach, Atul J. Butte, Geoffrey C. Gurtner
Format: article
Language:EN
Published: Nature Portfolio 2016
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Science
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Online Access:https://doaj.org/article/e3e19ba12cdd407ca10537b23a1ba94c
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Internet

https://doaj.org/article/e3e19ba12cdd407ca10537b23a1ba94c

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