Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats.

<h4>Background</h4>In this study, the neuroprotective effect of a novel nonpeptide AT2R agonist, C21, was examined in a conscious model of stroke to verify a class effect of AT2R agonists as neuroprotective agents.<h4>Methods and results</h4>Spontaneously hypertensive rats (S...

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Autores principales: Claudia A McCarthy, Antony Vinh, Alyson A Miller, Anders Hallberg, Mathias Alterman, Jennifer K Callaway, Robert E Widdop
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/e3e2ac36c92a4fceb1b89559b68dc59f
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