Affinity and competition for TBP are molecular determinants of gene expression noise
TATA boxes in gene promoters are associated with high level of cell-to-cell variation in gene expression. Through integration of multiple data sets, the authors now provide insights into how the interactions of TBP with DNA and other proteins can lead to noisy expression.
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Main Authors: | Charles N. J. Ravarani, Guilhem Chalancon, Michal Breker, Natalia Sanchez de Groot, M. Madan Babu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/e3e7cf8d13c14af0856ae4db82ef2db9 |
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