Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis

Brain morphogenesis is an important process contributing to higher-order cognition, however our knowledge about its biological basis is largely incomplete. Here, authors analyzed 118 neuroanatomical parameters in 1,566 mutant mouse lines to identify 198 genes whose disruptions yield neuroanatomical...

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Autores principales: Stephan C. Collins, Anna Mikhaleva, Katarina Vrcelj, Valerie E. Vancollie, Christel Wagner, Nestor Demeure, Helen Whitley, Meghna Kannan, Rebecca Balz, Lauren F. E. Anthony, Andrew Edwards, Hervé Moine, Jacqueline K. White, David J. Adams, Alexandre Reymond, Christopher J. Lelliott, Caleb Webber, Binnaz Yalcin
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e3ec51735a66472fbde33afd3c90e626
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spelling oai:doaj.org-article:e3ec51735a66472fbde33afd3c90e6262021-12-02T16:57:09ZLarge-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis10.1038/s41467-019-11431-22041-1723https://doaj.org/article/e3ec51735a66472fbde33afd3c90e6262019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11431-2https://doaj.org/toc/2041-1723Brain morphogenesis is an important process contributing to higher-order cognition, however our knowledge about its biological basis is largely incomplete. Here, authors analyzed 118 neuroanatomical parameters in 1,566 mutant mouse lines to identify 198 genes whose disruptions yield neuroanatomical phenotypesStephan C. CollinsAnna MikhalevaKatarina VrceljValerie E. VancollieChristel WagnerNestor DemeureHelen WhitleyMeghna KannanRebecca BalzLauren F. E. AnthonyAndrew EdwardsHervé MoineJacqueline K. WhiteDavid J. AdamsAlexandre ReymondChristopher J. LelliottCaleb WebberBinnaz YalcinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stephan C. Collins
Anna Mikhaleva
Katarina Vrcelj
Valerie E. Vancollie
Christel Wagner
Nestor Demeure
Helen Whitley
Meghna Kannan
Rebecca Balz
Lauren F. E. Anthony
Andrew Edwards
Hervé Moine
Jacqueline K. White
David J. Adams
Alexandre Reymond
Christopher J. Lelliott
Caleb Webber
Binnaz Yalcin
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
description Brain morphogenesis is an important process contributing to higher-order cognition, however our knowledge about its biological basis is largely incomplete. Here, authors analyzed 118 neuroanatomical parameters in 1,566 mutant mouse lines to identify 198 genes whose disruptions yield neuroanatomical phenotypes
format article
author Stephan C. Collins
Anna Mikhaleva
Katarina Vrcelj
Valerie E. Vancollie
Christel Wagner
Nestor Demeure
Helen Whitley
Meghna Kannan
Rebecca Balz
Lauren F. E. Anthony
Andrew Edwards
Hervé Moine
Jacqueline K. White
David J. Adams
Alexandre Reymond
Christopher J. Lelliott
Caleb Webber
Binnaz Yalcin
author_facet Stephan C. Collins
Anna Mikhaleva
Katarina Vrcelj
Valerie E. Vancollie
Christel Wagner
Nestor Demeure
Helen Whitley
Meghna Kannan
Rebecca Balz
Lauren F. E. Anthony
Andrew Edwards
Hervé Moine
Jacqueline K. White
David J. Adams
Alexandre Reymond
Christopher J. Lelliott
Caleb Webber
Binnaz Yalcin
author_sort Stephan C. Collins
title Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
title_short Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
title_full Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
title_fullStr Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
title_full_unstemmed Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
title_sort large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e3ec51735a66472fbde33afd3c90e626
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