Generic wound signals initiate regeneration in missing-tissue contexts

Some wounds trigger regeneration, while others simply heal but how this is regulated is unclear. Here, by manipulating ERK and Wnt signalling pathways, the authors create headless planarians and finless zebrafish and show that wounds that normally only trigger wound healing can activate regeneration...

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Bibliographic Details
Main Authors: Suthira Owlarn, Felix Klenner, David Schmidt, Franziska Rabert, Antonio Tomasso, Hanna Reuter, Medhanie A. Mulaw, Sören Moritz, Luca Gentile, Gilbert Weidinger, Kerstin Bartscherer
Format: article
Language:EN
Published: Nature Portfolio 2017
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Q
Online Access:https://doaj.org/article/e4121786dfd84d7e91076c345878d239
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