Targeting Bacillus anthracis toxicity with a genetically selected inhibitor of the PA/CMG2 protein-protein interaction

Abstract The protein-protein interaction between the human CMG2 receptor and the Bacillus anthracis protective antigen (PA) is essential for the transport of anthrax lethal and edema toxins into human cells. We used a genetically encoded high throughput screening platform to screen a SICLOPPS librar...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Abigail L. Male, Fedor Forafonov, Francesco Cuda, Gong Zhang, Siqi Zheng, Petra C. F. Oyston, Peng R. Chen, E. Diane Williamson, Ali Tavassoli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
R
Q
Acceso en línea:https://doaj.org/article/e4170e0bad4d42f1b4715b788d8d0feb
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!