Genetic variation of the IL-28B promoter affecting gene expression.

The current standard of care for the treatment of chronic hepatitis C is pegylated interferon-α (PEG-IFNα) and ribavirin (RBV). The treatment achieves a sustained viral clearance in only approximately 50% of patients. Recent whole genome association studies revealed that single nucleotide polymorphi...

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Autores principales: Masaya Sugiyama, Yasuhito Tanaka, Takaji Wakita, Makoto Nakanishi, Masashi Mizokami
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/e43f1a44991d43adadedf67633e8c03a
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