PRODUCTION OF RECOMBINANT PROTEIN CRM197 IN ESCHERICHIA COLI

The CRM197 is a non-toxic mutant of diphtheria toxin having a single amino acid substitution of a glycine for a glutamic acid in position 52. Being naturally nontoxic, CRM197 is a promising adjuvant and ideal carrier protein for conjugate vaccines. Typically, production of diphtheria toxin and some...

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Main Authors: I. V. Dukhovlinov, E. A. Fedorova, E. G. Bogomolova, O. A. Dobrovolskaya, E. N. Chernyaeva, R. I. Al-Shekhadat, A. S. Simbirtsev
Format: article
Language:RU
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2015
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Online Access:https://doaj.org/article/e4a638dcdd2c4d69b05b095dff972fac
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