Tuning of the Lethal Response to Multiple Stressors with a Single-Site Mutation during Clinical Infection by <italic toggle="yes">Staphylococcus aureus</italic>

ABSTRACT The agr system of Staphylococcus aureus promotes invasion of host tissues, and as expected, agents that block agr quorum sensing have anti-infective properties. Paradoxically, agr-defective mutants are frequently recovered from patients, especially those persistently infected with S. aureus...

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Bibliographic Details
Main Authors: Krishan Kumar, John Chen, Karl Drlica, Bo Shopsin
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
agr
Online Access:https://doaj.org/article/e4bb76f99bda47de95822f184f80c069
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