Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation

Leukaemia cells resident in the bone marrow niche are often resistant to conventional therapies. In this study, the authors develop light-sensitive, polymeric, retinoic acid-containing nanoparticles that are able to modulate the differentiation of resistant leukaemia cells bothin vitro and in vivo.

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Detalles Bibliográficos
Autores principales: Carlos Boto, Emanuel Quartin, Yijun Cai, Alberto Martín-Lorenzo, María Begoña García Cenador, Sandra Pinto, Rajeev Gupta, Tariq Enver, Isidro Sánchez-García, Dengli Hong, Ricardo Pires das Neves, Lino Ferreira
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e4bdd43ae19445c3acce605c66e63d91
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