Single cell polarity in liquid phase facilitates tumour metastasis
Polarisation of metastasising cancer cells in circulation has not been investigated before. Here the authors identify single cell polarity as a distinct polarisation state of single cells in liquid phase, and show that perturbing single cell polarity affects attachment, adhesion, transmigration and...
Guardado en:
Autores principales: | Anna Lorentzen, Paul F. Becker, Jan Kosla, Massimo Saini, Kathrin Weidele, Paolo Ronchi, Corinna Klein, Monika J. Wolf, Felix Geist, Bastian Seubert, Marc Ringelhan, Daniela Mihic-Probst, Knud Esser, Marko Roblek, Felix Kuehne, Gaia Bianco, Tracy O’Connor, Quentin Müller, Kathleen Schuck, Sebastian Lange, Daniel Hartmann, Saskia Spaich, Olaf Groß, Jochen Utikal, Sebastian Haferkamp, Martin R. Sprick, Amruta Damle-Vartak, Alexander Hapfelmeier, Norbert Hüser, Ulrike Protzer, Andreas Trumpp, Dieter Saur, Nachiket Vartak, Christoph A. Klein, Bernhard Polzer, Lubor Borsig, Mathias Heikenwalder |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e4d4ca03df544a909e2ed53aef5fd83a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
TGFβ Signaling in Myeloid Cells Promotes Lung and Liver Metastasis Through Different Mechanisms
por: Cristina Stefanescu, et al.
Publicado: (2021) -
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma
por: Melanie Werner-Klein, et al.
Publicado: (2018) -
The influence of attention and reward on the learning of stimulus-response associations
por: Devavrat Vartak, et al.
Publicado: (2017) -
An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer
por: Dilara Sahin, et al.
Publicado: (2020) -
A Novel Measurement Standard for Surface Roughness on Involute Gears
por: Felix Steinmeyer, et al.
Publicado: (2021)