Exposure-dependent control of malaria-induced inflammation in children.

In malaria-naïve individuals, Plasmodium falciparum infection results in high levels of parasite-infected red blood cells (iRBCs) that trigger systemic inflammation and fever. Conversely, individuals in endemic areas who are repeatedly infected are often asymptomatic and have low levels of iRBCs, ev...

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Autores principales: Silvia Portugal, Jacqueline Moebius, Jeff Skinner, Safiatou Doumbo, Didier Doumtabe, Younoussou Kone, Seydou Dia, Kishore Kanakabandi, Daniel E Sturdevant, Kimmo Virtaneva, Stephen F Porcella, Shanping Li, Ogobara K Doumbo, Kassoum Kayentao, Aissata Ongoiba, Boubacar Traore, Peter D Crompton
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/e4e9b922a4e742aba4bc1050044c01c3
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