Genome-wide prediction of DNase I hypersensitivity using gene expression

A map of the activities of all genomic regulatory elements across cell types and conditions would be a tremendous resource. The computational method introduced here predicts genome-wide accessible sites from gene expression data and allows the authors to build a database of regulatory element activi...

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Bibliographic Details
Main Authors: Weiqiang Zhou, Ben Sherwood, Zhicheng Ji, Yingchao Xue, Fang Du, Jiawei Bai, Mingyao Ying, Hongkai Ji
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/e4f7d3f666b34099a714b5e909d78b44
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Summary:A map of the activities of all genomic regulatory elements across cell types and conditions would be a tremendous resource. The computational method introduced here predicts genome-wide accessible sites from gene expression data and allows the authors to build a database of regulatory element activities using publicly available transcriptome data.