Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types

Single cell profiling yields high dimensional data of very large numbers of cells, posing challenges of visualization and analysis. Here the authors introduce a method for analysis of mass cytometry data that can handle very large datasets and allows their intuitive and hierarchical exploration.

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Autores principales: Vincent van Unen, Thomas Höllt, Nicola Pezzotti, Na Li, Marcel J. T. Reinders, Elmar Eisemann, Frits Koning, Anna Vilanova, Boudewijn P. F. Lelieveldt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e50b0012ac854b22b12f11d3326c67c4
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spelling oai:doaj.org-article:e50b0012ac854b22b12f11d3326c67c42021-12-02T15:38:51ZVisual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types10.1038/s41467-017-01689-92041-1723https://doaj.org/article/e50b0012ac854b22b12f11d3326c67c42017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01689-9https://doaj.org/toc/2041-1723Single cell profiling yields high dimensional data of very large numbers of cells, posing challenges of visualization and analysis. Here the authors introduce a method for analysis of mass cytometry data that can handle very large datasets and allows their intuitive and hierarchical exploration.Vincent van UnenThomas HölltNicola PezzottiNa LiMarcel J. T. ReindersElmar EisemannFrits KoningAnna VilanovaBoudewijn P. F. LelieveldtNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vincent van Unen
Thomas Höllt
Nicola Pezzotti
Na Li
Marcel J. T. Reinders
Elmar Eisemann
Frits Koning
Anna Vilanova
Boudewijn P. F. Lelieveldt
Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
description Single cell profiling yields high dimensional data of very large numbers of cells, posing challenges of visualization and analysis. Here the authors introduce a method for analysis of mass cytometry data that can handle very large datasets and allows their intuitive and hierarchical exploration.
format article
author Vincent van Unen
Thomas Höllt
Nicola Pezzotti
Na Li
Marcel J. T. Reinders
Elmar Eisemann
Frits Koning
Anna Vilanova
Boudewijn P. F. Lelieveldt
author_facet Vincent van Unen
Thomas Höllt
Nicola Pezzotti
Na Li
Marcel J. T. Reinders
Elmar Eisemann
Frits Koning
Anna Vilanova
Boudewijn P. F. Lelieveldt
author_sort Vincent van Unen
title Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
title_short Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
title_full Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
title_fullStr Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
title_full_unstemmed Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
title_sort visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e50b0012ac854b22b12f11d3326c67c4
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