In-vivo thrombolytic efficacy of RGD modified protein-polymer conjugated urokinase nanogels

It has been shown that an arginine-glycine-aspartic acid (RGD) modified pH-triggered delivery system for the urokinase-type plasminogen activator (uPA) is resistant to enzymatic degradation and improves thrombolytic ability in vitro. Herein, we aimed to compare the thrombolytic efficacies of uPA-oxi...

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Autores principales: Xia Liu, Ling-Li Jin, Ling-Ling Zhao, Ya-Chao Wang, Liping Zhang, Zheng-Zheng Huang, Hai-Qiang Jin, Jun-Ying Liu, Zhen-Jiang Liang, Xuan Liu, Hui Tan, Li-Jie Ren
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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RGD
Acceso en línea:https://doaj.org/article/e53d9dc9da2a45e1b10a237189b0f372
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