In-vivo thrombolytic efficacy of RGD modified protein-polymer conjugated urokinase nanogels

In-vivo thrombolytic efficacy of RGD modified protein-polymer conjugated urokinase nanogels

It has been shown that an arginine-glycine-aspartic acid (RGD) modified pH-triggered delivery system for the urokinase-type plasminogen activator (uPA) is resistant to enzymatic degradation and improves thrombolytic ability in vitro. Herein, we aimed to compare the thrombolytic efficacies of uPA-oxi...

Full description

Saved in:
Bibliographic Details
Main Authors: Xia Liu, Ling-Li Jin, Ling-Ling Zhao, Ya-Chao Wang, Liping Zhang, Zheng-Zheng Huang, Hai-Qiang Jin, Jun-Ying Liu, Zhen-Jiang Liang, Xuan Liu, Hui Tan, Li-Jie Ren
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
RGD
pH-triggered delivery
Targeted thrombolysis
Stroke
Blood-brain barrier
Polymers and polymer manufacture
TP1080-1185
Online Access:https://doaj.org/article/e53d9dc9da2a45e1b10a237189b0f372
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/e53d9dc9da2a45e1b10a237189b0f372

Similar Items