Benchmarking microbiome transformations favors experimental quantitative approaches to address compositionality and sampling depth biases

Here, the authors use simulated quantitative gut microbial communities to benchmark the performance of 13 common data transformations in determining diversity as well as microbe-microbe and microbe-metadata associations, finding that quantitative approaches incorporating microbial load variation out...

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Bibliographic Details
Main Authors: Verónica Lloréns-Rico, Sara Vieira-Silva, Pedro J. Gonçalves, Gwen Falony, Jeroen Raes
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/e544f190337b4f3d9572dcc00f19fd3d
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