Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

Diketopiperazine derivatives are bioactive molecules with scaffold formed by the condensation of two amino acids. Here, Yao et al. mine the genomes of Streptomyces strains and identify new biosynthetic machinery for drimentines biosynthesis, which includes cyclodipeptide synthase, prenyltransferase,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tingting Yao, Jing Liu, Zengzhi Liu, Tong Li, Huayue Li, Qian Che, Tianjiao Zhu, Dehai Li, Qianqun Gu, Wenli Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e546f0a9c8004b52ba5bf6cf5e299ecd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e546f0a9c8004b52ba5bf6cf5e299ecd
record_format	dspace
spelling	oai:doaj.org-article:e546f0a9c8004b52ba5bf6cf5e299ecd2021-12-02T14:39:10ZGenome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery10.1038/s41467-018-06411-x2041-1723https://doaj.org/article/e546f0a9c8004b52ba5bf6cf5e299ecd2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06411-xhttps://doaj.org/toc/2041-1723Diketopiperazine derivatives are bioactive molecules with scaffold formed by the condensation of two amino acids. Here, Yao et al. mine the genomes of Streptomyces strains and identify new biosynthetic machinery for drimentines biosynthesis, which includes cyclodipeptide synthase, prenyltransferase, and terpene cyclase.Tingting YaoJing LiuZengzhi LiuTong LiHuayue LiQian CheTianjiao ZhuDehai LiQianqun GuWenli LiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tingting Yao Jing Liu Zengzhi Liu Tong Li Huayue Li Qian Che Tianjiao Zhu Dehai Li Qianqun Gu Wenli Li Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
description	Diketopiperazine derivatives are bioactive molecules with scaffold formed by the condensation of two amino acids. Here, Yao et al. mine the genomes of Streptomyces strains and identify new biosynthetic machinery for drimentines biosynthesis, which includes cyclodipeptide synthase, prenyltransferase, and terpene cyclase.
format	article
author	Tingting Yao Jing Liu Zengzhi Liu Tong Li Huayue Li Qian Che Tianjiao Zhu Dehai Li Qianqun Gu Wenli Li
author_facet	Tingting Yao Jing Liu Zengzhi Liu Tong Li Huayue Li Qian Che Tianjiao Zhu Dehai Li Qianqun Gu Wenli Li
author_sort	Tingting Yao
title	Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
title_short	Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
title_full	Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
title_fullStr	Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
title_full_unstemmed	Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
title_sort	genome mining of cyclodipeptide synthases unravels unusual trna-dependent diketopiperazine-terpene biosynthetic machinery
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e546f0a9c8004b52ba5bf6cf5e299ecd
work_keys_str_mv	AT tingtingyao genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT jingliu genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT zengzhiliu genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT tongli genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT huayueli genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT qianche genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT tianjiaozhu genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT dehaili genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT qianqungu genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery AT wenlili genomeminingofcyclodipeptidesynthasesunravelsunusualtrnadependentdiketopiperazineterpenebiosyntheticmachinery
_version_	1718390744738168832

Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

Ejemplares similares