Glycogen content regulates peroxisome proliferator activated receptor-∂ (PPAR-∂) activity in rat skeletal muscle.

Performing exercise in a glycogen depleted state increases skeletal muscle lipid utilization and the transcription of genes regulating mitochondrial β-oxidation. Potential candidates for glycogen-mediated metabolic adaptation are the peroxisome proliferator activated receptor (PPAR) coactivator-1α (...

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Autores principales: Andrew Philp, Matthew G MacKenzie, Micah Y Belew, Mhairi C Towler, Alan Corstorphine, Angela Papalamprou, D Grahame Hardie, Keith Baar
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/e5d7fa7b55c24790b3f6d96a1ece2973
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