The anti-cancer effects of itraconazole in epithelial ovarian cancer

The anti-cancer effects of itraconazole in epithelial ovarian cancer

Abstract We assessed the anti-proliferative activity of itraconazole using an EOC cell line (SKOV3ip1) and endothelial cell lines (HUVEC & SVEC4-10). We also examined angiogenesis (VEGFR2, p-ERK, p-PLCr1/2), hedgehog (Gli1, Ptch1, SMO), and mTOR (pS6K1) signaling pathways to determine the mechan...

Full description

Saved in:
Bibliographic Details
Main Authors: Chel Hun Choi, Ji-Yoon Ryu, Young-Jae Cho, Hye-Kyung Jeon, Jung-Joo Choi, Kris Ylaya, Yoo-Young Lee, Tae-Joong Kim, Joon-Yong Chung, Stephen M. Hewitt, Byoung-Gie Kim, Duk-Soo Bae, Jeong-Won Lee
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e5ea0a7065c94edd9f99bdda3322c4ca
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items